Pregnancy failure, also known as miscarriage, refers to the loss of the fetus before the 20th week of gestation. Approximately 10 to 20 percent of recognized pregnancies come to an end in miscarriage. However, the actual figure is possibly higher due to the reason that numerous miscarriages take place in early pregnancy. In terms of medicine, miscarriage is known as spontaneous abortion. Mostly pregnancy failure occurs due to conditions which we can’t control. It is also sometimes really hard to find out its exact reason.

By finding out the major possible reasons for pregnancy failure, you can raise the likelihood of having a happy and healthy pregnancy. This article will be really helpful in this regard.


Following are some major possible reasons for pregnancy failure:-


About 70 percent of the pregnancy failures that occur in the starting 12 weeks are the result of the defect in the genes of the fetus. During the process of fertilization, the egg and the sperm carry 23 chromosomes simultaneously to form the best-matched pairs. Even a minor defect in this process can lead to a chromosomal abnormality.

The baby’s unique characteristics are recognized by the genes which are present in the chromosomes. With a damaged or incorrect number of chromosomes, the baby is unable to grow normally. Abnormal chromosomes can result in various problems such as molar pregnancy, partial moral pregnancy, and blighted ovum.


There are two types of thyroid diseases; hypothyroidism (very low) and hyperthyroidism (very high). Thyroid disorder is one of the major causes of miscarriage and infertility issues. According to research, when the functioning of the women’s thyroid is low, her body strives to compensate by manufacturing hormones that can ultimately repress ovulation. On the contrary, a thyroid that manufactures a lot of hormones can hinder the estrogen’s capability to perform its function which causes anomalous uterine bleeding particularly for surrogate mothers and madri surrogate.


At some times, the women’s body is unable to produce enough quantities of progesterone, the hormone which is significant to assist the uterine lining to hold up the fetus and support the placenta take grip. Raised prolactin levels can cause a change in the usual development of the uterine lining. Medication may play a role in the improvement of the odds of an effective succeeding pregnancy.


Some common infections take place during the period of conception. These include the infections of urinary tract, skin, and respiratory tract but they are not harmful to the unborn child. However, there are some infections that move toward the fetus before or in the course of birth and can harm the fetus or can lead to premature birth or pregnancy failure.

Listeriosis is a bacterial infection that raises the chances of pregnancy failure, preterm labor, and stillbirth. This infection may be present in newborn babies; however, the symptoms may appear after some weeks after birth.

Another harmful infection is Toxoplasmosis which is a protozoal infection that can lead to fetus loss, pregnancy failure, and severe birth defects.


A relatively less important factor of pregnancy failure is physical complexities within the pregnant woman. This typically takes place in the second and third trimesters. The examples may include the following:-

  • Several women are born with a rare uterine disorder known as septum which is a factor that leads to pregnancy failure.
  • Implantation or transportation of blood to the fetus can be obstructed by the Uterine Fibroids.
  • Rings of scar tissue can be developed in the uterus within the women due to second-time abortions or surgery. This scar tissue can hinder an egg from proper implantation and can also obstruct the flow of blood to the placenta.


In short, we can say that pregnancy failure is a stressful and depressing event for women suffering from this situation. In most instances, it can’t be avoided particularly when it results from the abnormalities of the chromosomes which are not consistent with life. However, it is suggested by the doctors to maintain a positive health status before you intend to conceive. There are many reasons for pregnancy failure but by taking care of the risk factors and by trying to minimize them, you can raise the possibility of having a healthy pregnancy.

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